What happened to “Charlie” started in his mother’s womb

Beginbeforebirth.org was put together by researchers from the Institute of Reproductive and Developmental Biology at Imperial College London. It posted the latest research on how a mother’s stress, caused by everything from domestic violence to natural disaster, affects what happens to the fetus developing in her womb.

The organization produced a series of games and videos, including Charlie’s Story, that look at a mother’s stress, how genes can be turned on and off depending on what’s happening in the mother’s social environment, and what the long-term consequences can be.

The site has a good section on epigenetics. You think the DNA you’re born with is your blueprint for life? Not quite. Your genes can be turned on and off, sometimes temporarily, sometimes permanently by what’s happening in your relationships. Getting a lot of verbal abuse and physical abuse from mom or dad? That’s setting off a flood of toxic stress hormones that are changing your DNA. And if the abuse is severe enough, you can pass the changes on to your children.

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